The mainstay of treatment of T1DM is insulin therapy. Many people wonder if there is an alternative treatment but to administer insulin is to correct the cause of T1DM - ie loss of insulin secretion.

However, there are always exceptions and, it could be said that, in some, very select patients with T1DM and an excepcional insulin secretion reserve - for example, a lean 45 year old patient that was diagnosed recently - can be well controlled with some lifestyle measures (ie healthy eating and exercising regularly). In our experience, most patients will eventually need some kind of insulin therapy - at least basal insulin once a day.

There is evidence that some patients may also benefit from the use of non-insulin drugs as adjuncts to insulin therapy, but therapeutic response is very heterogeneous. The most recent promising adjuvant therapy for T1DM were SGLT-2 inhibitors, but an increased risk of ketoacidosis associated with its use led to a curbing of enthusiasm.

To learn more about insulin therapy, folllow the links above.

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